Endocrine Abstracts

Introduction: Metabolic dysfunction-associated fatty liver disease (MAFLD) is present in a high percentage of obese patients undergoing bariatric surgery (BS), being an effective strategy for the remission of MAFLD. A significant proportion of patients still have steatohepatitis even after considerable weight loss and metabolic improvements. Liver biopsy remains the definitive test to classify a patient with steatohepatitis, but it is an invasive test. The use of non-invasive ...

Introduction: Vitamin D deficiency is a common health problem worldwide, particularly in elderly patients. Vitamin D is considered a key hormone in mineral and bone metabolism, as well as in functions such as the regulation of cell proliferation and differentiation, its immunoregulatory activity, its effect on the cardiovascular system and its neuroprotective and anti-ageing effects, among others. Hypovitaminosis D has been linked in multiple studies to a higher incidence and ...

Introduction: Differentiated thyroid cancer (DTC) represent 85- 90 % of all thyroid cancer cases. Most of these have an excellent prognosis with standard treatment. However, between 7 and 23% will develop distant metastases and, of these, more than 65% will become radioactive iodine-refractory. In some of these patients who are considered to be radioiodine-refractory with rapidly progressive or symptomatic disease, or in patients who are not candidates for other therapies, the...

Introduction: Neuroendocrine tumors are an heterogeneous group of neoplasms with increasing incidence and high survival. The therapies, could be have a negative impact on nutrition and pronogsis of these patients.Objetives: To analyze analytical and anthropometric parameters in relation to disease stage and survival.Material and methods: An observational, retrospective and cross-sectional study that includes patients with neuroendo...

Background: PREDIRCAM2 is a web platform for obesity treatment and follow-up. It contains modules for: dietary prescription and registry with nutritional analysis based on individualized and mediterranean dietary goals, physical activity prescription and tracking with individualized targets, and anthropometric tracking. An ongoing multicenter randomized clinical trial evaluates the intervention’s effectiveness in obesity treatment and cardio-metabolic-risk prevention....

Introduction: Assessing the effect of GLP 1 receptor agonist on metabolic control and weight loss in obesity and type 2 diabetes patients.Description of methods: A retrospective descriptive study involving type 2 diabetes patients and BMI >30 kg/m2, who started treatment with GLP-1-RAs during the years 2012–2014. Variables analyzed: weight and HbA1c at the begging, 6 months, 1 and 2 years; regimen at baseline and after GLP-1-RAs; inci...

Introduction: Myxoid tumors of the adrenal glands constitute an unusual entity and should be part of the differential diagnosis of atypical adenomas in the study of adrenal incidentaloma.Description of methods: We report the finding of myxoid adrenal adenoma in left adrenal gland in a 38-year-old woman.Case: PMH: Active smoker. Non hypertension, type 2 diabetes or dyslipidemia. No constitutional symptoms.Phys...

Introduction: It has been described that early post-operative cortisol value <2 μg/dl might predict long-term remission while ACTH value has been less described.Objective: To study early post-operative ACTH and cortisol levels in Cushing’s disease patients as predictor factor of long-term remission.Patients: 61 consecutive patients (12 men/49 women), mean age 42.6 years (17–86 years) undergoing transphenoidal hyp...

Objective: The aim of this study was to evaluate maternal and perinatal outcomes before and after implementation of the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria for testing of gestational diabetes mellitus (GDM).Methods: This is a retrospective cohort study of women with GDM followed at a single university hospital. We compared maternal and neonatal outcomes of singleton pregnancies in women with GMD before (from...

Introduction: Hydroxymethylglutaric aciduria is a rare metabolic disease that is caused by the deficiency of the enzyme 3-hydroxy-3-methylglutaryl-CoA lyase, which participates in the metabolism of leucine and in the formation of ketone bodies. The symptomatology usually occurs in the first two years of life and consists of nausea, vomiting, diarrhea, hypotoniaanddepressed level of consciousness. Metabolic acidosis occurs during crises as a result of the accumulation of metabo...